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The study found that L-carnitine uptake improves glycemic markers through reduction of fasting blood glucose, glycosylated hemoglobin, and HOMA-IR (homeostatic model assessment for insulin resistance) with lesser effects on insulin levels in the serum

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Besides the colon cancer cells, the elevation of p70S6K1 phosphorylation is also observed in breast cancer MCF7 cells treated with an IGF-1R inhibitor, OSI-906